PhD Program

We’re one of the few programs in the country that trains in structure/function—where students learn at the molecular level and from the ground up to find the cause and cure of disease. In our program, students take the lead in their research and frequently collaborate with different labs. And the research? It’s cutting-edge in a supportive environment. See how we train the next generation of biochemists.

Research Interest Areas

  • DNA Biochemistry
  • RNA Biochemistry
  • Lipids, lipoproteins, membrane transport,
    membrane structure and function
  • Protein structural biochemistry and biophysics
  • Mechanisms of signal transduction
  • Enzyme catalysis and regulation
  • Glycobiology, vaccine and antifungal

Let’s Talk About our Two Nobels in Chemistry

Considered the most prestigious award in the world, the Nobel Prize was given to two faculty in the Department of Biochemistry. In 2015, Dr. Paul Modrich received the Nobel in Chemistry for his mechanistic studies in DNA repair and in 2012, Dr. Robert Lefkowitz won the Nobel in Chemistry for his discoveries that reveal the inner workings of an important family G protein-coupled receptors.

Lab Spotlight

Dr. Huanghe Yang and his lab study the molecular and cellular mechanisms of ion and lipid transport across cell membranes and their impact on health and treatment of disease. They focus on the recently discovered TMEM16 protein family—which include the calcium-activated ion channels and calcium-activated lipid scramblases. 

Recent News

Nobel prize winner George P. Smith completed his early award-winning research at Duke. While working in the lab of

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Duke has awarded Dr. Seok-Yong Lee the 2018 Outstanding Postdoc Mentor, recognizing him for his support and encouragement of trainees. He received his...

It is with great sadness we announce that Dr. Deborah A. Steege, Professor Emeritus of Biochemistry, passed away in Michigan...

Dr. Maria Schumacher was part of a team that found that beyond topoisomerases, an additional protein, GapR...

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