PhD Student, Bach Nguyen, Selected to Sit on International Student Advisory Board
Who better to help international students acclimate to life in Durham than others who are in the same position?
Biochemistry Faculty are Heavy Users of Cryo-EM
Duke Researchers, including Biochemistry faculty, have access to Cryo-EM that creates high-resolution images of the smallest pieces of proteins (at the atomic level).
The Lee Lab Determines the Structure of hRFC
hRFC is critical for the uptake of folate and chemotherapeutics. Using cryo-EM, the Lee Lab determined its structure with a cancer drug bound, helping to pave the way for future chemotherapeutic development.
Lee and Yokoyama Labs Reveal Chemical Logic of Chs Inhibition
Using cryo-EM, the Lee and Yokoyama labs collaborated on the structure of Chs2 from Candida albicans.
The Yang Lab Makes Discovery That’s Vital to Pregnancy and Human Existence
Fusion of millions of trophoblasts into a syncytiotrophoblast, a single gigantic cell in the placenta, is vital to pregnancy and human existence. The Yang Lab’s, Dr. Yang Zhang and colleagues discovered that it’s the TRPV4 calcium channel that operates TMEM16F scramblase and mediates this amazing cell fusion event. Read more in eLife
Duc Huynh Receives Ruth K. Broad Foundation Fellowship
Duc Huynh receives the one-year Ruth K. Broad Foundation Fellowship for his work on O-GlcNAc modification.
Adjunct Professor, Bettie Sue Masters, Recognized by the Medical College of Wisconsin
Bettie Sue Masters, Adjunct Professor in Biochemistry, was recently awarded an honorary D.
Lee Lab Uses cryo-EM and Thermal Titration Methods to See the Capsaicin Receptor Opening
Dr. Seok-Yong Lee & team found there are many conformations when RTx binds to TRPV1. With thermal titration and cryo-EM analysis, they elucidated the temporal order of conformations leading to TRPV1 opening. Read their research in Nature Communications.
Using Cryo-EM & Crystal Structures, Pei Zhou, PhD, and Team Study the Inner Workings of NPR1
By solving cryoEM and crystal structures of the plant protein NPR1 and its complex with the transcription factor TGA3, the Duke team led by Drs. Pei Zhou and Xinnian Dong could provide a possible boon for agriculture.