Metabolism and Biosynthesis

Metabolism and Biosynthesis

Many biosynthetic and metabolic pathways are linked to human diseases and are targets for therapeutic interventions. In understanding them we can address problems in human health at the biochemical, cellular, and organismal levels.

Our faculty study pathways in humans that are critical to sustaining the healthy growth of cells and tissues, and pathways in bacteria and fungi that are essential for survival and virulence or for producing small and macromolecules with important biological functions. Studies of these pathways frequently result in exciting basic science discoveries, including unique mechanisms of enzyme catalysis and pathway regulations. 

Our faculty focus on pathways for:

  • Naturally occurring antibiotics and other bio-active molecules
  • Cofactors
  • Glycans and their precursors
  • Lipids
  • Microbial cell wall