RNA and DNA

Nucleic acids are critical regulators of cellular functions across all domains of life. To understand how RNA and DNA contribute to physiological processes at the molecular, cellular, and organismal levels, it is important to study RNA and DNA biochemistry and to investigate their function, regulation, and biophysical properties.

OUR FACULTY STUDY A RANGE OF TOPICS IN RNA AND DNA INCLUDING:

  • Investigations into the structure and function of nucleic acids
  • DNA damage and mismatch repair
  • DNA replication
  • Transcription regulation
  • DNA and RNA modifications
  • RNA processing and post-transcriptional regulation
  • RNA and DNA 3D structure
  • RNA and DNA dynamics and folding
  • Protein: nucleic acid interactions
  • Genomic and transcriptomic analysis of gene expression

Faculty

Adjunct Professor in the Department of Biochemistry
James B. Duke Distinguished Professor of Medicine
Consulting Professor in the Department of Medicine
James B. Duke Distinguished Professor of Biochemistry
Professor Emeritus of Biochemistry
Assistant Professor of Biochemistry
James B. Duke Distinguished Professor of Biochemistry
Professor of Biochemistry
James B. Duke Distinguished Professor of Medicine
Nanaline H. Duke Distinguished Professor of Biochemistry