News

Dr. Ken Kreuzer simplifies the complex in his new textbook.

A close collaboration between The Yang Lab, The Mikati Lab at Duke Pediatrics, and The Cui Lab at Washington University, St. Louis uncovered the molecular pathophysiology of a new human BK channel mutation associated with dystonia, and discovered novel therapeutics to mitigate this common movement disorder. Read about their findings in Movement Disorders. 

Next-gen biochemist, Brady Travis, Brady solved the structures of the transcription complexes that control Francisella tularensis’ virulence

To combat antibiotic resistance, Drs. Seok-Yong Lee and Ellene Mashalidis wrote a review paper to describe several recent structures of MraY and its human paralog, GlcNAc-1-P-transferase, providing critical paths forward for the design of potent and selective MraY inhibitors. Read more

Congratulations to Seok-Yong Lee, PhD, for his promotion to Professor with tenure, effective 1 July 2020. Please read more about the outstanding research on membrane transport proteins that is happening in the Lee Laboratory by visiting his website. 

Congratulations to Brady Travis for receiving the Ruth L. Kirschstein National Research Service Award (NRSA) for promising predoctoral students to develop into productive independent research scientists.

In Trends in Biochemical Sciences, Dr. Seok-Yong Lee & Ying Yin wrote a review paper to describe structural features of TRMP8 that underlie distinguishing functions in its unique cooling-compound sensing of TRPM8 making it unique compared to TRPV1 and other TRP channel members. Read more

Postdoc, Dr. Ping Dong, receives fellowship to study how an ion channel mutation causes epilepsy and movement disorders.

The Yang Lab's new discovery gives insights into the function of TMEM16F CaPLSase in trophoblast fusion and placental development. Read more

How do human cells deal with stressors and nutrient depletion? Drs. Pei Zhou, Ashley Chi, and team solved the mystery when they discovered the inner workings of MESH1. Read more