News

A team of Duke researchers found that transcription factors have a tendency to bind strongly to “mismatched” sections of DNA, which might be a way in which random mutations become a problem that leads to disease, including cancer. Read more

Atul Rangadurai wins Chancellor's Award for Research Excellence.

In 2019-20, nine BiochemistryPhDs defended their dissertations

An international collaboration that included the labs of Drs. Alberto Bartesaghi and Gustavo Silva found a new regulation of protein production in cells under oxidative stress using cryo-EM. 

To prevent putting the mentor relationship on the back burner, graduate students developed an engaging calendar to keep this important relationship moving forward. Read more

Dr. Ken Kreuzer simplifies the complex in his new textbook.

A close collaboration between The Yang Lab, The Mikati Lab at Duke Pediatrics, and The Cui Lab at Washington University, St. Louis uncovered the molecular pathophysiology of a new human BK channel mutation associated with dystonia, and discovered novel therapeutics to mitigate this common movement disorder. Read about their findings in Movement Disorders. 

Next-gen biochemist, Brady Travis, Brady solved the structures of the transcription complexes that control Francisella tularensis’ virulence

Biochemistry leadership makes diversity statements.

To combat antibiotic resistance, Drs. Seok-Yong Lee and Ellene Mashalidis wrote a review paper to describe several recent structures of MraY and its human paralog, GlcNAc-1-P-transferase, providing critical paths forward for the design of potent and selective MraY inhibitors. Read more