New Calcium Binding Site Found in TMEM16A
The Yang Lab’s, Son Le, found a new calcium-binding site in TMEM16A and demonstrated its long-range allosteric gating mechanism. This helps explain TMEM16A’s involvement in secretion, smooth muscle contraction, pain sensation, & cancer progression. Read more in Cell Reports.
Dr. Hashim Al-Hashimi Named ISMAR Fellow
Dr. Hashim Al-Hashimi elected Fellow of the International Society of Magnetic Resonance.
New Research Helps Understand TMEM16F's Role in Cancer & Ischemia
Dr. Pengfei Liang of the Yang Lab discovered that the once elusive activity of the scramblase and ion channel, TMEM16F, is regulated by intracellular pH in a calcium-dependent manner. Read more in the Journal of General Physiology.
A New Memoir From Nobel Prize Winner Dr. Robert Lefkowitz
With the untimely death of three collaborators, Dr. Robert Lefkowitz went on to win the Nobel Prize in Chemistry. Read an excerpt from his new memoir, "A Funny Thing Happened on the Way to Stockholm The Adrenaline-Fueled Adventures of an Accidental Scientist" in ASBMB Today.
Al-Hashimi Named Biophysical Society Fellow
Dr. Hashim Al-Hashimi was noted for his "excellence in science" specifically developing and deploying NMR methods that reveal the dynamic nature of nucleic acids and their functional complexes. Read more
Mike Boyce, PhD, Receives New Mathers Foundation Funding
Mike Boyce, PhD, is expanding his work to research a novel approach to understanding common lung diseases. Read more
Research From Blanca Rodriguez Published in Scientific Reports
New research from Blanca Rodriguez and Meta Kuehn, PhD, reports the presence of RNA and DNA molecules in extracellular membrane vesicles secreted by the human pathogen, Staphylococcus aureus and reveals a novel mechanism of host-pathogen interactions. Read more
New Insights on the Impact of 2'-O-Methylation on Alternative RNA Conformational States
In Nucleic Acids Research, Drs. Hala Abou Assi, Christopher Holley, Hashim Al-Hashimi and team unveil that 2'-O-methylation (Nm) preferentially stabilizes alternative secondary structures where Nm-modified nucleotides are paired, increasing the abundance and lifetime of low-populated short-lived excited states up to 10-fold. Read more
Jason Arne Does Two-On-Two Interview
Duke's Advanced Professional Degree Consulting Club's Jason Arne teamed up with Richard Hollenbach to do a two-on-two interview with Duke Grad School alums and Boston Consulting Group consultants, Drs. Billy Gerhard and Dane Sequeira. Learn how they became interested in consulting and why a PhD is a good fit for BCG. Read more
Meet One of the Next Generation of Biochemists, Skyler Cochrane
Skyler develops and tests novel inhibitors of LpxH and investigates how to improve the permeation of antibiotics across the double membrane of highly infectious, gram-negative bacteria.