Pei Zhou (Primary)
NMR of Macromolecules, Physical Biochemistry, Protein Structure, Structural Biology
For the latest information on the Zhou Lab, please visit our website.
270 Sands Building, Research Drive, Box 3711, Durham, NC 27710
The Zhou lab focuses on the elucidation of the structure, dynamics, and function of protein-protein and protein-ligand interactions and their roles in various cellular processes. Our current efforts are directed toward enzymes and protein complexes involved in bacterial membrane biosynthesis and pathogenesis, co-transcriptional regulation, and translesion DNA synthesis. Along with these efforts, we are also developing novel antibiotics and cancer therapeutics based on insights from structural and dynamics studies. In order to achieve these goals, the Zhou lab integrates a variety of biochemical and biophysical tools, including NMR, X-ray crystallography, enzymology, and others. Our lab has also played a major role in development and application of cutting-edge NMR technologies, including automated resonance assignment and structural analysis tools and high-resolution, high-dimensional spectral reconstruction techniques.
|1997-1998||Lilly Predoctoral Fellowship, Harvard University, Cambridge, MA|
|2001||Whitehead Scholar, Duke University, Durham, NC|
|2015||Wang Tianjuan Lectureship, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences|
PhD, Harvard University 1998