Kenichi Yokoyama (Primary)

Assistant Professor of Biochemistry
Yokoyama Lab, Primary Faculty
Research Interests: 

Enzyme Mechanisms, Radical Reactions, EPR spectroscopy, Natural Product Chemistry and Chemical Biology

For the latest information on the Yokoyama Lab, please visit our website.

Lab Location
Nanaline Duke Room 233A
Office Location

Nanaline Duke 233A, Durham, NC 27710

(919) 684-8848
Education

PhD Tokyo Institute of Technology, 2008
Postdoc MIT, 2011

Publications
  1. Wei, Y, Mathies, G, Yokoyama, K, Chen, J, Griffin, RG, and Stubbe, J. "A Chemically Competent Thiosulfuranyl Radical on the Escherichia coli Class III Ribonucleotide Reductase." Journal of the American Chemical Society 136, no. 25 (June 25, 2014): 9001-9013.  Full Text
  2. Hover, BM, Loksztejn, A, Ribeiro, AA, and Yokoyama, K. "Identification of a cyclic nucleotide as a cryptic intermediate in molybdenum cofactor biosynthesis." J Am Chem Soc 135, no. 18 (May 8, 2013): 7019-7032.  Full Text  Link to Item
  3. Wörsdörfer, B, Conner, DA, Yokoyama, K, Livada, J, Seyedsayamdost, M, Jiang, W, Silakov, A, Stubbe, J, Bollinger, JM, and Krebs, C. "Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer." Journal of the American Chemical Society 135, no. 23 (2013): 8585-8593.  Full Text
  4. Ando, N, Brignole, EJ, Zimanyi, CM, Funk, MA, Yokoyama, K, Asturias, FJ, Stubbe, J, and Drennan, CL. "Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase." Proceedings of the National Academy of Sciences of the United States of America 108, no. 52 (2011): 21046-21051.  Full Text
  5. Yokoyama, K, Smith, AA, Corzilius, B, Griffin, RG, and Stubbe, J. "Equilibration of tyrosyl radicals (Y 356·, Y 731·, Y 730·) in the radical propagation pathway of the Escherichia coli class Ia ribonucleotide reductase." Journal of the American Chemical Society 133, no. 45 (2011): 18420-18432.  Full Text