Research Interests: My research is concerned with studying the dynamics of single enzyme molecules using fluorescence microscopy. Ensemble averaged measurements (normal enzyme kinetics) can mask some of the individual events that occur during catalysis.

 

Research Interests: Structure-function relationships of proteins; structure, function, and biosynthesis of oligosacchsrides

Research Interests: The research in our laboratory deals with the chemistry and biology of enzymes in which the element molybdenum is an essential constituent. Recent studies in the laboratory have led to the discovery and characterization of a novel prosthetic group, called molybdopterin, shown to be present in all Mo-containing enzymes (except nitrogenase) and is intimately involved in the catalytic activity associated with the molybdenum centers of the enzymes.

Research Interests: Gene Function and Regulation, Nucleic Acids Biochemistry, RNA Biochemistry