Arno L. Greenleaf

Professor of Biochemistry

PhosphoCTD-associating proteins and the functional organization of the nucleus.

Contact Information	Lab Location
Office Number: (919) 684-4030 Fax: (919) 685-8885 arno@biochem.duke.edu	Room 227 Nanaline Duke Building Office Room 228A

Mailing Address	Education
Department of Biochemistry Nanaline H. Duke Box 3711, DUMC Durham, NC 27710	Ph.D. (Harvard University, 1974)

Selected Publications

1. Bennett, C.B., Westmoreland, T.J., Verrier, C.S., Blanchette, C.A., Sabin, T.L., Phatnani, H.P., Mishina, Y.V., Huper, G., Selim, A.L., Madison, E.R., Bailey, D.D., Falae, A.I., Galli, A., Olson, J.A., Greenleaf, A.L., and Marks, J.R. 2008. “Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction.” PLoS ONE. 2008 Jan 16;3(1):e1448. More…

2. Phatnani, H.P. and Greenleaf, A.L. (2006). “Phosphorylation and functions of the RNA polymerase II CTD.” Genes and Development 20: 2922-2936. More…

3. Li, M., Phatnani, H. P., Guan, Z., Sage, H., Greenleaf, A., and Zhou, P. (2005). “Solution Structure of the SRI Domain of Human Set2 and Its Interaction with the PhosphoCTD.” Proc Natl Acad Sci U S A: in press. More…

4. Jones, J. C., Phatnani, H. P., Haystead, T. A., MacDonald, J. A., Alam, S. M., and Greenleaf, A. L(2004). ” C-terminal Repeat Domain Kinase I Phosphorylates Ser2 and Ser5 of RNA Polymerase II C-terminal Domain Repeats.” J Biol Chem 279: 24957-24964. More…

5. Phatnani, H. P., Jones, J. C., and Greenleaf, A. L. (2004). ” Expanding the Functional Repertoire of CTD Kinase I and RNA Polymerase II: Novel PhosphoCTD-Associating Proteins in the Yeast Proteome.” BIOCHEMISTRY 43: 15702-15719. More…

6. Greenleaf, A. (2003). ” Getting a grip on the CTD of Pol II.” Structure (Camb) 11: 900-902. More…

7. Carty, S. M., and Greenleaf, A. L. (2002). ” Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing.” Mol Cell Proteomics 1: 598-610. More…

8. Skaar, D. A., and Greenleaf, A. L. (2002). ” The RNA Polymerase II CTD Kinase CTDK-I Affects Pre-mRNA 3’ Cleavage/Polyadenylation through the Processing Component Pti1p.” Mol Cell 10: 1429-1439. More…

9. Goldstrohm, A. C., Greenleaf, A. L., and Garcia-blanco, M. A. (2001). ” Co-transcriptional Splicing of Pre-messenger RNAs: Considerations for the Mechanism of Alternative Splicing.” GENE 277: 31-47. More…