Macromolecular X-ray crystallography resource

Resource Director
Lorena S. Beese, Ph.D.
Office: 210A Nanaline Duke
Phone: (919) 681-5267
lsb@biochem.duke.edu
Resource Manager
James C. Phillips, Ph. D.
Office: B131 LSRC
Phone: 919-613-8890
jcphill@duke.edu

Duke has a fully-equipped X-ray crystallography facility that is located in the Levine Science Research Center (LSRC). The facility includes: two Rigaku area detectors, two Rigaku X-ray generators with mirror optics, a computer control room where diffraction data is processed, a wet lab where crystal trays can be set up, and two constant-temperature rooms with vibration-isolated platforms where crystals are grown. A full-time PhD-level manager maintains the equipment and provides assistance with data collection. Click here to take a tour of the facility.

Requesting Time

To request user time please check the calendars for open. To reserve time please email James Phillips or Marsha Brooks and request a time slot to be reserved in your name. You shoulld receive a confirmation of your request. Recheck the calendar to confirm the time was correctly reserved.

SER-CAT facility at the Advanced Photon Source at Argonne National Laboratory

The South East Regional Collaborative Access Team (SER-CAT) was organized in 1997 to establish a crystallography facility at the Advanced Photon Source (APS), a high brilliance 3rd generation synchrotron light source located at Argonne National Laboratory in Argonne, Illinois. The principal focus of the SER-CAT research is macromolecular crystallography. The SER-CAT facility will be a world-class experimental facility that promises to push the back the limits of macromolecular crystallography. The powerful and enhanced capabilities of the Advanced Photon Source will bring SER-CAT scientists and their laboratories to the pinnacle of their areas of research.

Duke University was one of the founding members of SER-CAT. The SER-CAT program currently consists of 21 member institutions across 10 states and the National Institutes of Health Intramural Program. SER-CAT is administrated through the Department of Biochemistry and Molecular Biology at the University of Georgia.

SER-CAT occupies Sector 22 of the Advanced Photon Source of the Argonne National Laboratory. Its goal is to construct an Insertion Device (ID) beamline and a Bending Magnet (BM) beamline, one year apart, for its users within a 4-year construction period. Beginning in November 2002, SER-CAT will provide its members with a comprehensive research facility, including a full complement of instrumentation, software, and support staff for high throughput data collection and processing from its first beamline.

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